SID Annual Meeting
2020-05-13 07:00:00
  • Home
    • Donate
  • Information
    • Claim your CME credits
    • Meeting Link, Program & Attendee User Guides
    • Abstract Book(s)
    • 2021 Meeting FAQ’s
    • Registration
    • Confirmed Speakers/Awardees
    • Poster/Exhibit Hall Information
    • 2021 Confirmed Exhibitors/Partners
    • Associate Group Programming
    • 2021 Registration Grants Information
    • Scientific Program Committee
    • Future Annual Meetings
  • Abstracts
    • 2021 Abstract Submission
      • Late-Breaking Abstract Submission
    • Abstract Categories
    • 2021 Abstract Outcomes
    • Presentation Information
  • Mon. 5/3
  • Tues. 5/4
  • Wed. 5/5
  • Thurs. 5/6
  • Fri. 5/7
  • Sat. 5/8
  • Home
    • Donate
  • Information
    • Claim your CME credits
    • Meeting Link, Program & Attendee User Guides
    • Abstract Book(s)
    • 2021 Meeting FAQ’s
    • Registration
    • Confirmed Speakers/Awardees
    • Poster/Exhibit Hall Information
    • 2021 Confirmed Exhibitors/Partners
    • Associate Group Programming
    • 2021 Registration Grants Information
    • Scientific Program Committee
    • Future Annual Meetings
  • Abstracts
    • 2021 Abstract Submission
      • Late-Breaking Abstract Submission
    • Abstract Categories
    • 2021 Abstract Outcomes
    • Presentation Information
  • Mon. 5/3
  • Tues. 5/4
  • Wed. 5/5
  • Thurs. 5/6
  • Fri. 5/7
  • Sat. 5/8
Dan Kaplan~low res

William Montagna Lecturer

Daniel Kaplan, MD/PhD

University of Pittsburgh

Title:  Cutaneous Neurons Modulate Skin Inflammation

Daniel H. Kaplan, MD/PhD is a Professor within the Department of Dermatology and Immunology, University of Pittsburgh (Kaplanlab.pitt.edu; @kaplanlab).  His research is dedicated to understanding the mechanisms that underlie skin immunity and the interplay of different immune cells types that reside in the skin.  As a graduate student at Washington University, St. Louis he participated in the re-invigoration of the concept of tumor immunosurveillance by observing an increased frequency of skin tumors in immunodeficient mice.  During his fellowship/postdoc at Yale University, he developed a number of genetically modified mouse lines with a selective deficiency of Langerhans cells (LC) and showed that these cells have the unexpected capacity to suppress tissue immune responses.  As an Assistant and later Associate professor at the University of Minnesota, his lab found that LC and dermal dendritic cells have unique functions in the development of anti-pathogen responses.  More recently, his lab has focused on the contribution of non-hematopoetic cells to skin immunity.   In particular, they have found that keratinocytes participate in maintaining epidermal residence of both LC and CD8+ resident memory T cells through the transactivation of autocrine TGFβ.  This mechanism shapes both skin-resident and circulating memory T cell pools.  The lab has also found that TRPV1-expressing neurons in the skin can directly sense and respond to C. albicans and are both necessary and sufficient for the development of cutaneous Type-17 innate immune responses.  These neurons not only participate in local innate immunity but also alert adjacent skin sites to potential danger in a process termed “anticipatory immunity”.  Current efforts in the lab focus on determining the regulation of KC-mediated TGFβ transactivation, exploring the immune functions other subtypes of cutaneous neurons and mapping-out the precise intracellular networks driving different types of local inflammation.

https://www.immunology.pitt.edu/person/daniel-kaplan-md-phd

 

About the Lectureship:

The William Montagna Lecture is given annually at the SID’s Annual/Virtual Meeting.  The award is intended to honor and reward young investigators with primary emphasis given to researchers in skin biology.

Other Speakers

Akiko Iwasaki is seen on Friday April 26 2013 at Yale University. (Kike Calvo/AP Images for HHMI)Julius Stone Lecturer
NHSportrait-fix-1Herman Beerman Lecturer
Version 2Eugene M. Farber Lecturer
2021 Meg ChrenNaomi M. Kanof Lecturer
Paul Khavari Photo for RothmanStephen Rothman Memorial Awardee
OH, JuliaState-of-the-Art Plenary Lecture I
YH_officeState-of-the-Art Plenary Lecture II
brownell-hi resState-of-the-Art Plenary Lecture III
Donald_Glass_headshotState-of-the-Art Plenary Lecture IV
VUMC employee headshots on January 11, 2021. Photos by Donn Jones/Vanderbilt University Medical CenterState-of-the-Art Plenary Lecture V
Shuai Xu MD ~ hi resState-of-the-Art Plenary Lecture VI
MTO-Stuart IsettSpecial Guest Speaker
SID_logo_PPlenary Sessions I-IV
Twitter Highlights
  • LEO Foundation Award deadline extended to January 29! https://t.co/eNkZQqeJ51
    1 day ago
  • RT @ISID2023Tokyo: Calling young skin scientists! LEO Foundation Award 2023 Self-nomination deadline is 25 Jan. https://t.co/8YAwc9OhJs Awa…
    9 days ago

Follow SID on Twitter

© 2021 Society for Investigative Dermatology, All rights reserved.